which changes the total amount of protein produced. Thus, genes that affect the final form and expression amount of another gene can be influential in the formation of the phenotype derived from ...

Any time two different genes contribute to a single phenotype and their effects are ... Sometimes, two genes that each have the same role in protein production can substitute for each other.

Changing the sequence of DNA can change the amino acids that make up the protein. This could have huge ... This diagram shows the DNA when all of the genes are switched off: In different cells ...

RIKEN researchers have discovered how a single mutation in one gene can simultaneously result in two symptoms—a severely ...

Researchers used integrated Mendelian randomization in a cohort of over 247,000 individuals to identify 62 plasma proteins associated with breast cancer risk. Nine high-confidence targets, including ...

Colorectal cancer (CRC), a type of cancer that affects the large intestine and rectum, is one of the leading causes of cancer ...

Depending on the definition, a gene may be considered a stretch of DNA that acts as instructions for protein production. Regions of DNA that do not code for proteins may also be considered genes if ...

New research shows how the Eurasian common shrew (Sorex araneus) changes its brain and bodily size throughout the year. The study, published online in eLife, reveals how changes in gene expression ...

What happens next can vary. The standard Cas9 protein cuts the DNA at the target. When the cut is repaired, mutations are introduced that usually disable a gene. This is by far the most common use ...

Specifically, in this study, the researchers identified a 3-bp deletion in the coding region of GTPBP2, a gene that encodes a G-protein expressed in several tissues—including the canine retina.