Human lung fibroblasts stimulated with TGF-β1 to detect extracellular collagen I (pink), alpha-smooth muscle actin (α-SMA) (green), and cell nuclei (blue) as a measure of matrix production and ...
Fibrosis, resulting from excess extracellular matrix (ECM) deposition, is a feature of adipose tissue (AT) dysfunction and obesity-related insulin resistance.
In a recent study published in Scientific Reports, researchers reported that microfibril-associated protein 5 (MFAP5) mediates wound healing through its pro-fibrotic effect by modulating collagen ...