Panel a: This is a cartoon "ribbon" diagram of the structure of Rumi in complex with ... Panel b: Disease-related Rumi mutations abolish the enzyme's activity relative to the "wild type" (WT ...

If people could design very efficient enzymes from scratch, you could solve many important problems,” said UCSB chemistry ...

Discover Celoce, a natural enzyme from Brazil that could revolutionize biofuel production by efficiently breaking down ...

Thus, understanding the interplay between structure, dynamics and function of enzymes in solution is an important goal in modern biochemistry. Generations of students have been introduced to this ...

The active site of an enzyme has a unique three-dimensional structure that allows it to bind to a specific substrate, much like a lock and key. This specificity ensures that enzymes catalyze only the ...

virtually no information of how enzyme structure relates to function is needed. The next frontier may be "molecular breeding" for the engineering of new pathways and even entire viral and ...

Using high-resolution X-ray crystallography (2.0 Å), the team resolved the enzyme’s structure, revealing a six-bladed β-propeller catalytic domain linked to a carbohydrate-binding module (CBM ...