An illustration of a self-assembling protein nanoparticle (SApNP) displaying Ebola virus surface proteins. This vaccine strategy is designed to help the immune system more effectively and respond to ...
Genetic mutations called "escape variants" in the deadly Ebola virus appear to block the ability of antibody-based treatments to ward off infection, according to a team of U.S. Army scientists and ...
A recent study published in PLOS Pathogens examined two newly identified nanobodies, Nanosota-EB1 and Nanosota-EB2, as potential inhibitors of the Ebola virus. The research evaluated the ability of ...
The Institute for Research in Biomedicine (IRB), affiliated to the Università della Svizzera italiana (USI), and Humabs BioMed SA, a Swiss antibody therapeutics company, have identified, isolated and ...
The model on the left shows how the Ebola virus stalk has a compact conformation, which blocks the site where mAb 3A6 would bind. The model on the right shows how this portion of the stalk can adopt ...
Scientists have developed a tool to narrow down potential host species of filoviruses like Ebola and better prioritize wildlife surveillance. Bats are widely recognized as the primary hosts of ...