Nature1y
The Role of Methylation in Gene Expression
Not all genes are active at all times. DNA methylation is one of several epigenetic mechanisms that cells use to control gene expression. This straightforward experiment demonstrated that it was ...
EMBO Press12d
DNA methylation changes during acute COVID-19 are associated with long-term transcriptional dysregulation in patients’ airway epithelial cells
Concurrent analysis of whole-genome DNA methylation and single-cell RNA sequencing data from COVID-19 patients and controls ...
Nature1y
Linking DNA methylation and histone modification: patterns and paradigms
The basic pattern of genomic DNA methylation is established at the time of embryo implantation through a wave of de novo methylation, but CpG islands are protected through a mechanism that ...
The Scientist2y
Brush Up: What Is Bisulfite Sequencing and How Do Researchers Use It to Study DNA Methylation?
DNA methylation is a fundamental epigenetic mechanism in which a methyl group is added onto a nucleotide, commonly cytosine. DNA methylation affects many biological processes, including gene ...
BioWorld12d
Methylated DNA epigenetic map pinpoints on-and-off switches of genes
The first complete DNA methylation atlas of 39 human cell types reveals which genes can talk or are silenced, depending on whether their sequence is linked to methyl group epigenetic modification that ...