However, DNMT1 rapidly scans DNA and deposits methyl groups on newly synthesized DNA, opposite methyl groups present on the old DNA strand. This results in faithful replication of methylation ...
The paper C.R. Merry et al., “DNMT1-associated long non-coding RNAs regulate global gene expression and DNA methylation in colon cancer,” Hum Mol Genet, 24:6240-53, 2015. DNA methylation is a critical ...
The basic pattern of genomic DNA methylation is established at the time of embryo implantation through a wave of de novo methylation, but CpG islands are protected through a mechanism that ...
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