From cancer-fighting Taxol to fragrant rose oils, plant terpenoids shape our world in surprising ways. Scientists are now ...

Many computational methods have been developed that predict the regioselectivity of metabolism by drug metabolising isoforms of the Cytochrome P450 class of enzymes (P450) [1-5]. Here we describe ...

The omega-3 long-chain polyunsaturated fatty acids, DHA and EPA, and their specific bioactive products derived from the cytochrome P450 pathway, can influence choroidal neovascularization and vascular ...

Tyrosine kinase inhibitors (TKIs) are metabolized via the cytochrome P450 pathway, which may be associated with the production of toxic intermediates. These drugs can also induce oxidative stress and ...

University of Massachusetts (UMass) Amherst food scientists have identified a set of metabolic enzymes that are upregulated in colon cancer-bearing mice and in human colon cancer cells, and could ...