Instead of having two copies of each chromosome, as is typical for normal cells, the cancer cells had anywhere from one to as many as five or six copies; and sometimes there were parts of chromosomes ...

Figure 2c shows portions of the karyotype in which translocation chromosomes were placed next to their normal homologues. At least 30 rearrangements were observed in this cell, and some of the ...

Each human cell contains 23 pairs of chromosomes that carry DNA within their nucleus. The X and Y chromosomes, commonly referred to as the sex chromosomes, are one such pair. They determine the ...

Humans have 46 chromosomes in each cell, which is divided into pairs of ... division happens early in development—either after a normal egg and sperm unite or when some cells lose the extra ...

Like mitosis, meiosis is a form of eukaryotic cell division. However, these two processes distribute genetic material among the resulting daughter cells in very different ways. Mitosis creates two ...

An international team of researchers co-led by Job Dekker, PhD, at UMass Chan Medical School, have identified rules that tell cells how to fold DNA into the tightly packed, iconic X-shaped chromosomes ...

In normal cells, telomeres shorten as people age because replication does not proceed efficiently near the ends of the chromosomes. However, Coats plus patients have shorter telomeres than ...

In normal cells, telomeres shorten as people age because replication does not proceed efficiently near the ends of the chromosomes. However, Coats plus patients have shorter telomeres than ...

“This work is really important because the X chromosome has largely been excluded from genetic ... The researchers found that, across all ages, the proportion of an individual’s blood cells that ...

Dormant genes on the X chromosome may reawaken ... in on gene activity in cells of the hippocampus, a key memory center in the brain that tends to shrink with normal aging and cognitive decline ...

Our lab studies the mechanism of eukaryotic chromosome replication. Chromosomes are the carriers of the genetic and epigenetic information and faithful chromosome replication is of fundamental ...