Highly ordered chromatin structures also cause replication problems, as they are very compact and wrap around histone proteins, and in turn result in highly ordered structures. All of these can ...

Interestingly, H2A.Z does not take its place during replication when the chromatin structure is established. Instead, the chromatin remodeling complex SWR1 catalyzes an ATP-dependent exchange of ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For ...

Based on these results, the UAB researchers propose that the chromatin filament of the chromosomes ... as well as for DNA ...

View Full Profile. Learn about our Editorial Policies. Lis and Gilmour focused on identifying proteins that bound to specific chromatin sites to understand the mechanisms of gene regulation. To do so, ...

The Whitehouse lab is broadly interested in understanding how chromatin functions in the regulation of cellular processes such as DNA replication, gene transcription and epigenetics. We focus on ...