Background: Growing body of evidence suggests that Parkinson's disease (PD) is associated with oxidative damage via iron accumulation in the substantia nigra (SN). Low ceruloplasmin (CP)-ferroxidase ...

HealthDay News — In patients with sickle cell anemia (SCA), urinary ceruloplasmin (CP) may complement urinary free hemoglobin as a noninvasive biomarker for chronic kidney disease (CKD), according to ...

Copper, a reddish metal that occurs naturally not only in soil, water, sediment and air, but also in plants and animals, is an essential element for all known living organisms, including human beings.

Physiology : Ceruloplasmin is a feroxidase enzyme found in the blood of humans. It carries eight atoms of copper and plays a very important role in iron metabolism. The gene responsible for encoding ...

Copper is a unique essential trace element because it can participate in a wide variety of redox reactions, which allows it to function in numerous biologic processes. Key examples include ...

What if a simple blood test could detect liver cancer before it shows symptoms or escapes existing scans? cell-free ceruloplasmin (CP) mRNA in blood might be the one we’ve been waiting for—especially ...

A study of a copper enzyme that misfolds and malfunctions in copper- and iron-metabolism diseases indicates that it can't be fixed simply by inducing the copper-deficient misfolded version to take up ...