The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

The presence of anti-CD4 autoantibodies in treatment-naive patients with advanced HIV was associated with a decreased rate of CD4 reconstitution following ART initiation.

Measuring CD4 T-cells is important in helping healthcare providers determine the stage and likely outcome of HIV infection. While they are no longer used to determine when HIV therapy should be ...

Gilead's CROI 2025 data highlights Biktarvy's sustained HIV/HBV suppression, lenacapavir's efficacy, and vesatolimod's safety ...

A clinical trial suggests Lenacapavir, a yearly injection, could revolutionise HIV prevention by offering long-term ...

Non-Hodgkin's lymphoma (NHL) is a cancer of special white blood cells called lymphocytes ... but you can get it even if you have a high CD4 count and your HIV hasn't yet become AIDS.

CD4-positive T cells are a subtype of lymphocyte ... A key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T cell. Inflammatory immune cells ...

SAN FRANCISCO -- Most patients with HIV who received two broadly neutralizing antibodies (bNAbs) after pausing antiretroviral ...

More information: Costin Tomescu et al, Gene-modified NK cells expressing CD64 and preloaded with HIV-specific BNAbs target autologous HIV-1–infected CD4+ T cells by ADCC, The Journal of ...

Coreceptors are responsible for a crucial step between Env binding to the receptor CD4 and membrane fusion mediated by the gp41 fusion peptide. Determinants of HIV cell tropism & chemokine ...

Theratechnologies (THTX) presented data from a real-world, observational, registry study demonstrating the efficacy and safety of ibalizumab in ...