The San Francisco 49ers are set to pay Brock Purdy a massive contract extension, but SFGATE columnist Drew Magary isn't sure ...

The San Francisco 49ers are set to wrap up the 2024 regular season this Sunday at State Farm Stadium, where they will face the Arizona Cardinals. Which ...

Arizona State Sun Devils’ Cam Skattebo could be a dream addition for the San Francisco 49ers as they seek to bolster their ...

When the ball dropped in 2024, the San Francisco 49ers were amongst the NFL's elite and primed for a deep postseason run. A ...

James Cook and the Buffalo Bills are the largest favorite of Sunday's NFL slate facing the New ... night when the Detroit Lions face the San Francisco 49ers. The Lions were 3.5-point road ...

In the final game of Week 17, the San Francisco 49ers will play host to the Detroit Lions on "Monday Night Football." San ...

Detroit Lions and San Francisco 49ers meet on Monday Night Football in NFL Week 17. Find live updates, score summary, game ...

Ahead of a massive showdown with the rival Minnesota Vikings to wrap up the regular season, the Detroit Lions flexed their NFC might on Monday night to take down the San Francisco 49ers.

While some teams still try to make the playoffs, several NFL franchises could change their fortunes with a loss in Week 18, ...

Kyler Murray has started all 16 games for the Cardinals in his first full season back following knee surgery a couple seasons ...